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Theranostic Liposomes with Hypoxia-Activated Prodrug to Effectively Destruct Hypoxic Tumors Post-Photodynamic Therapy

Photodynamic therapy (PDT), a noninvasive cancer therapeutic method triggered by light, would lead to severe tumor hypoxia after treatment. Utilizing a hypoxia-activated prodrug, AQ4N, which only shows toxicity to cancer cells under hypoxic environment, herein, a multipurpose liposome is prepared by...

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Enregistré dans:
Détails bibliographiques
Publié dans:ACS Nano
Auteurs principaux: Feng, Liangzhu, Cheng, Liang, Dong, Ziliang, Tao, Danlei, Barnhart, Todd E., Cai, Weibo, Chen, Meiwan, Liu, Zhuang
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372701/
https://ncbi.nlm.nih.gov/pubmed/28027442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.6b07525
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