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Lin28 Induces Resistance to Anti-Androgens Via Promotion of AR Splice Variant Generation
BACKGROUND: Prostate cancer (PCa) is androgen-dependent initially and progresses to a castration-resistant state after androgen deprivation therapy. Treatment options for castration-resistant PCa include the potent second-generation anti-androgen enzalutamide or CYP17A1 inhibitor abiraterone. Recent...
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| Publicado en: | Prostate |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5372699/ https://ncbi.nlm.nih.gov/pubmed/26714839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23134 |
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