Lin28 Promotes Growth of Prostate Cancer Cells and Activates the Androgen Receptor

Prostate cancer (CaP) progresses to a castration-resistant state assisted by multifold molecular changes, most of which involve activation of the androgen receptor (AR). Having previously demonstrated the importance of the Lin28/let-7/Myc axis in CaP, we tested the hypothesis that Lin28 is overexpre...

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Detalhes bibliográficos
Main Authors: Tummala, Ramakumar, Nadiminty, Nagalakshmi, Lou, Wei, Zhu, Yezi, Gandour-Edwards, Regina, Chen, Hong-Wu, Evans, Christopher P., Gao, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702743/
https://ncbi.nlm.nih.gov/pubmed/23790802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.03.011
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