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Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity
Tenofovir (TFV) is an antiviral drug approved for treating Human Immunodeficiency Virus (HIV) and Hepatitis B. TFV is administered orally as the prodrug tenofovir disoproxil fumarate (TDF) which then is deesterified to the active drug TFV. TFV induces nephrotoxicity characterized by renal failure an...
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Publicado no: | Int J Mol Sci |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5372547/ https://ncbi.nlm.nih.gov/pubmed/28257038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030531 |
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