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Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity

Tenofovir (TFV) is an antiviral drug approved for treating Human Immunodeficiency Virus (HIV) and Hepatitis B. TFV is administered orally as the prodrug tenofovir disoproxil fumarate (TDF) which then is deesterified to the active drug TFV. TFV induces nephrotoxicity characterized by renal failure an...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Murphy, Rachel A., Stafford, Reagan M., Petrasovits, Brooke A., Boone, Megann A., Valentovic, Monica A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372547/
https://ncbi.nlm.nih.gov/pubmed/28257038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030531
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