Tumor Cell-Derived Microvesicles Induced Not Epithelial-Mesenchymal Transition but Apoptosis in Human Proximal Tubular (HK-2) Cells: Implications for Renal Impairment in Multiple Myeloma

Renal impairment (RI) is one of the hallmarks of multiple myeloma (MM) and carries a poor prognosis. Microvesicles (MVs) are membrane vesicles and play an important role in disease progression. Here, we investigated the role of MVs derived from MM cells (MM-MVs) in RI of MM. We found that MM-MVs sig...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Zhao, Aiqi, Kong, Fancong, Liu, Chun-Jie, Yan, Guoxin, Gao, Fei, Guo, Hao, Guo, An-Yuan, Chen, Zhichao, Li, Qiubai
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372529/
https://ncbi.nlm.nih.gov/pubmed/28264449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030513
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