Characterization of a mutation in a family with saposin B deficiency: a glycosylation site defect.

Saposins are small, heat-stable glycoproteins required for the hydrolysis of sphingolipids by specific lysosomal hydrolases. Saposins A, B, C, and D are derived by proteolytic processing from a single precursor protein named prosaposin. Saposin B, previously known as SAP-1 and sulfatide activator, s...

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Bibliographic Details
Main Authors: Kretz, K A, Carson, G S, Morimoto, S, Kishimoto, Y, Fluharty, A L, O'Brien, J S
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53725/
https://ncbi.nlm.nih.gov/pubmed/2320574
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