Associations of LEP, CRH, ICAM-1, and LINE-1 methylation, measured in saliva, with waist circumference, body mass index, and percent body fat in mid-childhood

BACKGROUND: Genetics explains a small proportion of variance in body mass index at the population level. Epigenetics, commonly measured by gene methylation, holds promise for understanding obesity risk factors and mechanisms. METHODS: Participants were 431 adolescents aged 10–15 years. BMI z-score,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Epigenetics
Main Authors: Dunstan, Jocelyn, Bressler, Joseph P., Moran, Timothy H., Pollak, Jonathan S., Hirsch, Annemarie G., Bailey-Davis, Lisa, Glass, Thomas A., Schwartz, Brian S.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372250/
https://ncbi.nlm.nih.gov/pubmed/28360946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0327-5
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