Spatial and molecular resolution of diffuse malignant mesothelioma heterogeneity by integrating label-free FTIR imaging, laser capture microdissection and proteomics

Diffuse malignant mesothelioma (DMM) is a heterogeneous malignant neoplasia manifesting with three subtypes: epithelioid, sarcomatoid and biphasic. DMM exhibit a high degree of spatial heterogeneity that complicates a thorough understanding of the underlying different molecular processes in each sub...

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Publicat a:Sci Rep
Autors principals: Großerueschkamp, Frederik, Bracht, Thilo, Diehl, Hanna C., Kuepper, Claus, Ahrens, Maike, Kallenbach-Thieltges, Angela, Mosig, Axel, Eisenacher, Martin, Marcus, Katrin, Behrens, Thomas, Brüning, Thomas, Theegarten, Dirk, Sitek, Barbara, Gerwert, Klaus
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372163/
https://ncbi.nlm.nih.gov/pubmed/28358042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44829
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