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Randomised controlled trial comparing ofatumumab to rituximab in children with steroid-dependent and calcineurin inhibitor-dependent idiopathic nephrotic syndrome: study protocol

INTRODUCTION: Oral steroids induce remission in about 90% of children with idiopathic nephrotic syndrome (INS), which is characterised by severe proteinuria and hypoalbuminaemia. Some children become steroid-dependent (SD) and require addition of calcineurin inhibitors (CNI) to maintain remission. S...

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Bibliographic Details
Published in:BMJ Open
Main Authors: Ravani, Pietro, Bonanni, Alice, Ghiggeri, Gian Marco
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372102/
https://ncbi.nlm.nih.gov/pubmed/28314744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2016-013319
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