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Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis

INTRODUCTION: Gabapentin has been extensively prescribed off-label for psychiatric indications, with little established evidence of efficacy. Gabapentin and pregabalin, a very similar drug with the same mechanism of action, bind to a subunit of voltage-dependent calcium channels which are implicated...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Houghton, Kerensa T, Forrest, Alexandra, Awad, Amine, Atkinson, Lauren Z, Stockton, Sarah, Harrison, Paul J, Geddes, John R, Cipriani, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372050/
https://ncbi.nlm.nih.gov/pubmed/28348186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2016-013433
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