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Acute Oral Toxicity of Tetrodotoxin in Mice: Determination of Lethal Dose 50 (LD50) and No Observed Adverse Effect Level (NOAEL)

Tetrodotoxin (TTX) is starting to appear in molluscs from the European waters and is a hazard to seafood consumers. This toxin blocks sodium channels resulting in neuromuscular paralysis and even death. As a part of the risk assessment process leading to a safe seafood level for TTX, oral toxicity d...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Abal, Paula, Louzao, M. Carmen, Antelo, Alvaro, Alvarez, Mercedes, Cagide, Eva, Vilariño, Natalia, Vieytes, Mercedes R., Botana, Luis M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371830/
https://ncbi.nlm.nih.gov/pubmed/28245573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9030075
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