B Cell Tolerance to Deiminated Histones in BALB/c, C57BL/6, and Autoimmune-Prone Mouse Strains

Deimination, a posttranslational modification of arginine to citrulline carried out by peptidylarginine deiminases, may compromise tolerance of self-antigens. Patients with connective tissue autoimmunity, particularly rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), or Felty’s syndrome...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Dwivedi, Nishant, Hedberg, Annica, Zheng, Ying Yi, Neeli, Indira, Satoh, Minoru, Morel, Laurence, Rekvig, Ole Petter, Radic, Marko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371714/
https://ncbi.nlm.nih.gov/pubmed/28424695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00362
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