Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatments

PURPOSE: Modification of mucous cell density and gel-forming mucin production are established hallmarks of mucosal diseases. Our aim was to develop and validate a mouse model to study live goblet cell density in pathological situations and under pharmacological treatments. METHODS: We created a repo...

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Bibliographic Details
Published in:PLoS One
Main Authors: Portal, Céline, Gouyer, Valérie, Gottrand, Frédéric, Desseyn, Jean-Luc
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371386/
https://ncbi.nlm.nih.gov/pubmed/28355261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174764
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