Associations of estradiol levels and genetic polymorphisms of inflammatory genes with the risk of ischemic stroke

BACKGROUND: Estrogen plays an important role as an anti-inflammatory and neuroprotective agent in ischemic stroke. In this study, we analyzed the effect of a polygenic risk score (PRS) constructed using inflammatory genes and estradiol levels on the risk of ischemic stroke. METHODS: This case-contro...

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Dettagli Bibliografici
Pubblicato in:J Biomed Sci
Autori principali: Hsieh, Yi-Chen, Hsieh, Fang-I, Chen, Yih-Ru, Hu, Chaur-Jong, Jeng, Jiann-Shing, Tang, Sung-Chun, Chi, Nai-Fang, Lin, Huey-Juan, Lien, Li-Ming, Peng, Giia-Sheun, Chiou, Hung-Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371181/
https://ncbi.nlm.nih.gov/pubmed/28351426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0332-1
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