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Comparison of the morphine-sparing effect of intraoperative dexmedetomidine with and without loading dose following general anesthesia in multiple-fracture patients: A prospective, randomized, controlled clinical trial

Intraoperative dexmedetomidine (DEX) with or without loading dose both promote morphine-sparing effect in patient-controlled analgesia on postoperative acute pain. However, the contribution of the loading dose to this effect is largely unknown, especially in long-lasting surgeries. The present study...

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Publicado en:Medicine (Baltimore)
Main Authors: Zhao, Jin-Ning, Kong, Min, Qi, Bin, Ge, Dong-Jian
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Health 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370813/
https://ncbi.nlm.nih.gov/pubmed/27537587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000004576
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