Regulatory changes in presynaptic cholinergic function assessed in rapid autopsy material from patients with Alzheimer disease: implications for etiology and therapy.

Brain regions from patients with or without Alzheimer disease (AD) were obtained within 2 hr of death and examined for indices of presynaptic cholinergic function. Consistent with loss of cholinergic projections, cerebral cortical areas involved in AD exhibited decreased choline acetyltransferase (a...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Slotkin, T A, Seidler, F J, Crain, B J, Bell, J M, Bissette, G, Nemeroff, C B
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1990
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53707/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2320567/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2452
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