Age-Related Changes in Nucleus Pulposus Mesenchymal Stem Cells: An In Vitro Study in Rats

The functions of mesenchymal stem cells (MSCs) appear to decline with age due to cellular senescence, which could reduce the efficacy of MSCs-based therapies. Recently, MSCs have been identified in the nucleus pulposus, which offers great potential for intervertebral disc (IVD) repair. However, this...

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Veröffentlicht in:Stem Cells Int
Hauptverfasser: Zhao, Yachao, Jia, Zhiwei, Huang, Shanshan, Wu, Yaohong, Liu, Longgang, Lin, Linghan, Wang, Deli, He, Qing, Ruan, Dike
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370515/
https://ncbi.nlm.nih.gov/pubmed/28396688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6761572
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