Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense

Obligate intracellular Chlamydia trachomatis replicate in a membrane-bound vacuole called inclusion, which serves as a signaling interface with the host cell. Here, we show that the chlamydial deubiquitinating enzyme (Cdu) 1 localizes in the inclusion membrane and faces the cytosol with the active d...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:eLife
Autores principales: Fischer, Annette, Harrison, Kelly S, Ramirez, Yesid, Auer, Daniela, Chowdhury, Suvagata Roy, Prusty, Bhupesh K, Sauer, Florian, Dimond, Zoe, Kisker, Caroline, Hefty, P Scott, Rudel, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370187/
https://ncbi.nlm.nih.gov/pubmed/28347402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21465
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares