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Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling

Derlin-1 has been found to be overexpressed in several human cancers. However, its clinical significance and biological roles in bladder cancer remain unexplored. Here, we found that Derlin-1 was upregulated in 38.6% (58/150) cases of cancer samples. The rate of Derlin-1 overexpression was higher in...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Dong, Qianze, Fu, Lin, Zhao, Yue, Tan, Shutao, Wang, Enhua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370022/
https://ncbi.nlm.nih.gov/pubmed/28178653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15001
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