Heterogeneity in sarcoma cell lines reveals enhanced motility of tetraploid versus diploid cells

Soft tissue sarcomas with complex genomics are very heterogeneous tumors lacking simple prognosis markers or targeted therapies. Overexpression of a subset of mitotic genes from a signature called CINSARC is of bad prognosis, but the significance of this signature remains elusive. Here we precisely...

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Vydáno v:Oncotarget
Hlavní autoři: Jemaà, Mohamed, Abdallah, Samer, Lledo, Gwendaline, Perrot, Gaelle, Lesluyes, Tom, Teyssier, Catherine, Roux, Pierre, van Dijk, Juliette, Chibon, Frederic, Abrieu, Ariane, Morin, Nathalie
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369993/
https://ncbi.nlm.nih.gov/pubmed/28035071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14291
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