The subclonal structure and genomic evolution of oral squamous cell carcinoma revealed by ultra-deep sequencing

Recent studies suggest that head and neck squamous cell carcinomas are very heterogeneous between patients; however the subclonal structure remains unexplored mainly due to studies using only a single biopsy per patient. To deconvolute the clonal structure and describe the genomic cancer evolution,...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Tabatabaeifar, Siavosh, Thomassen, Mads, Larsen, Martin J, Larsen, Stine R, Kruse, Torben A, Sørensen, Jens A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369985/
https://ncbi.nlm.nih.gov/pubmed/28157713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15014
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