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Optimization and evaluation of astragalus polysaccharide injectable thermoresponsive in-situ gels

The objective of this study was to develop an injectable in situ forming gel system based on Poloxamer for sustained release of Astragalus polysaccharide (APS), thus achieved once or twice administration instead of frequent dosing during long-term treatment. The optimal formulation is 10 g APS, 18 g...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Yu, Zugong, Guo, Fanxi, Guo, Yangyang, Zhang, Zhenrui, Wu, Feng, Luo, Xiaoqing
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369758/
https://ncbi.nlm.nih.gov/pubmed/28350799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173949
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