GT198 (PSMC3IP) germline variants in early-onset breast cancer patients from hereditary breast and ovarian cancer families

GT198, located 470 kb downstream of BRCA1, encodes for the nuclear PSMC3-interacting protein, which functions as co-activator of steroid hormone-mediated gene expression, and is involved in RAD51 and DMC1-mediated homologous recombination during DNA repair of double-strand breaks. Recently, germline...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Genes Cancer
Κύριοι συγγραφείς: Schubert, Stephanie, Ripperger, Tim, Rood, Melanie, Petkidis, Anthony, Hofmann, Winfried, Frye-Boukhriss, Hildegard, Tauscher, Marcel, Auber, Bernd, Hille-Betz, Ursula, Illig, Thomas, Schlegelberger, Brigitte, Steinemann, Doris
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2017
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369655/
https://ncbi.nlm.nih.gov/pubmed/28435519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.132
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