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Calcium regulation of the human mitochondrial ATP-Mg/Pi carrier SLC25A24 uses a locking pin mechanism

Mitochondrial ATP-Mg/Pi carriers import adenine nucleotides into the mitochondrial matrix and export phosphate to the cytosol. They are calcium-regulated to control the size of the matrix adenine nucleotide pool in response to cellular energetic demands. They consist of three domains: an N-terminal...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Harborne, Steven P. D., King, Martin S., Crichton, Paul G., Kunji, Edmund R. S.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369052/
https://ncbi.nlm.nih.gov/pubmed/28350015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45383
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