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DNA alterations in Cd133+ and Cd133- tumour cells enriched from intra-operative human colon tumour biopsies

BACKGROUND: Tumour stem cells are considered important to promote disease progression, recurrence and treatment resistance following chemotherapy in colon cancer. However, genomic analyses of colorectal cancer have mainly been performed on integrated tumour tissue consisting of several different cel...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Cervantes-Madrid, Diana, Wettergren, Yvonne, Falk, Peter, Lundholm, Kent, Asting, Annika G.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369016/
https://ncbi.nlm.nih.gov/pubmed/28347289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3206-8
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