Adventitial lymphatic capillary expansion impacts on plaque T cell accumulation in atherosclerosis

During plaque progression, inflammatory cells progressively accumulate in the adventitia, paralleled by an increased presence of leaky vasa vasorum. We here show that next to vasa vasorum, also the adventitial lymphatic capillary bed is expanding during plaque development in humans and mouse models...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rademakers, Timo, van der Vorst, Emiel P. C., Daissormont, Isabelle T. M. N., Otten, Jeroen J. T., Theodorou, Kosta, Theelen, Thomas L., Gijbels, Marion, Anisimov, Andrey, Nurmi, Harri, Lindeman, Jan H. N., Schober, Andreas, Heeneman, Sylvia, Alitalo, Kari, Biessen, Erik A. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368662/
https://ncbi.nlm.nih.gov/pubmed/28349940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45263
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