Human Amniocytes Are Receptive to Chemically Induced Reprogramming to Pluripotency

Restoring pluripotency using chemical compounds alone would be a major step forward in developing clinical-grade pluripotent stem cells, but this has not yet been reported in human cells. We previously demonstrated that VPA_AFS cells, human amniocytes cultivated with valproic acid (VPA) acquired fun...

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Publicado en:Mol Ther
Main Authors: Hawkins, Kate E., Moschidou, Dafni, Faccenda, Danilo, Wruck, Wasco, Martin-Trujillo, Alex, Hau, Kwan-Leong, Ranzoni, Anna Maria, Sanchez-Freire, Veronica, Tommasini, Fabio, Eaton, Simon, De Coppi, Paolo, Monk, David, Campanella, Michelangelo, Thrasher, Adrian J., Adjaye, James, Guillot, Pascale V.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Gene & Cell Therapy 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368475/
https://ncbi.nlm.nih.gov/pubmed/28153093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.11.014
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