Cardioprotective effect of metformin against doxorubicin cardiotoxicity in rats

OBJECTIVE: The clinical use of doxorubicin, which is a strong antineoplastic agent, is limited due to its cardiotoxic side effects. Metformin is a drug with antihyperglycemic effects, and it has been shown to have a cardioprotective effect on left ventricular function in experimental animal models o...

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Bibliographische Detailangaben
Veröffentlicht in:Anatol J Cardiol
Hauptverfasser: Argun, Mustafa, Üzüm, Kazım, Sönmez, Mehmet Fatih, Özyurt, Abdullah, Karabulut, Derya, Soyersarıca, Zeynep, Çilenk, Kübra Tuğçe, Unalmış, Sunay, Pamukcu, Özge, Baykan, Ali, Narin, Figen, Elmalı, Ferhan, Narin, Nazmi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Kare Publishing 2016
Schlagworte:
Original Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368431/
https://ncbi.nlm.nih.gov/pubmed/26642465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5152/akd.2015.6185
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