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Unconventional Targeting of a Thiol Peroxidase to the Mitochondrial Intermembrane Space Facilitates Oxidative Protein Folding

Thiol peroxidases are conserved hydrogen peroxide scavenging and signaling molecules that contain redox-active cysteine residues. We show here that Gpx3, the major H(2)O(2) sensor in yeast, is present in the mitochondrial intermembrane space (IMS), where it serves a compartment-specific role in oxid...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Kritsiligkou, Paraskevi, Chatzi, Afroditi, Charalampous, Georgia, Mironov, Aleksandr, Grant, Chris M., Tokatlidis, Kostas
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368413/
https://ncbi.nlm.nih.gov/pubmed/28297675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.053
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