The Anti-helminthic Compound Mebendazole Has Multiple Antifungal Effects against Cryptococcus neoformans

Cryptococcus neoformans is the most lethal pathogen of the central nervous system. The gold standard treatment of cryptococcosis, a combination of amphotericin B with 5-fluorocytosine, involves broad toxicity, high costs, low efficacy, and limited worldwide availability. Although the need for new an...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Joffe, Luna S., Schneider, Rafael, Lopes, William, Azevedo, Renata, Staats, Charley C., Kmetzsch, Lívia, Schrank, Augusto, Del Poeta, Maurizio, Vainstein, Marilene H., Rodrigues, Marcio L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368277/
https://ncbi.nlm.nih.gov/pubmed/28400768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00535
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