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Molecular mechanisms underlying deoxy‐ADP.Pi activation of pre‐powerstroke myosin
Myosin activation is a viable approach to treat systolic heart failure. We previously demonstrated that striated muscle myosin is a promiscuous ATPase that can use most nucleoside triphosphates as energy substrates for contraction. When 2‐deoxy ATP (dATP) is used, it acts as a myosin activator, enha...
Shranjeno v:
| izdano v: | Protein Sci |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5368076/ https://ncbi.nlm.nih.gov/pubmed/28097776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3121 |
| Oznake: |
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