Polytopic vaccination with a live-attenuated dengue vaccine enhances B-cell and T-cell activation, but not neutralizing antibodies

Dengue, caused by dengue viruses (DENVs), is the most common arboviral disease of humans. Several dengue vaccine candidates are at different stages of clinical development and one has been licensed. Inoculation with live-attenuated DENV constructs is an approach that has been used by vaccine develop...

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Publicado no:Heliyon
Main Authors: Hunsawong, Taweewun, Wichit, Sineewanlaya, Phonpakobsin, Thipwipha, Poolpanichupatam, Yongyuth, Klungthong, Chonticha, Latthiwongsakorn, Napaporn, Thaisomboonsuk, Butsaya, Im-erbsin, Rawiwan, Yoon, In-Kyu, Ellison, Damon W., Macareo, Louis R., Srikiatkhachorn, Anon, Gibbons, Robert V., Fernandez, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367862/
https://ncbi.nlm.nih.gov/pubmed/28393119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00271
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