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Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function

INTRODUCTION: Plasminogen activator inhibitor-1 (PAI-1), a major inhibitor of fibrinolysis, is associated with thrombosis, obesity, insulin resistance, dyslipidemia, and premature aging, which all are coexisting conditions of chronic obstructive pulmonary disease (COPD). The role of PAI-1 in COPD wi...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Waschki, Benjamin, Watz, Henrik, Holz, Olaf, Magnussen, Helgo, Olejnicka, Beata, Welte, Tobias, Rabe, Klaus F, Janciauskiene, Sabina
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367764/
https://ncbi.nlm.nih.gov/pubmed/28356730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S128689
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