The efficacy of lacosamide as monotherapy and adjunctive therapy in focal epilepsy and its use in status epilepticus: clinical trial evidence and experience

Lacosamide (LCM) is approved for anticonvulsive treatment in focal epilepsy and exhibits its function through the slow inactivation of voltage-gated sodium channels (VGSCs). LCM shows comparable efficacy with other antiepileptic drugs (AEDs) licensed in the last decade: in three randomized placebo-c...

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Bibliographic Details
Published in:Ther Adv Neurol Disord
Main Authors: Bauer, Sebastian, Willems, Laurent M., Paule, Esther, Petschow, Christine, Zöllner, Johann Philipp, Rosenow, Felix, Strzelczyk, Adam
Format: Artigo
Language:Inglês
Published: SAGE Publications 2016
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Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367645/
https://ncbi.nlm.nih.gov/pubmed/28382109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756285616675777
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