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Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism

The structures of muscle thin filaments reconstituted using skeletal actin and cardiac troponin and tropomyosin have been determined with and without bound Ca(2+) using electron microscopy and reference-free single particle analysis. The resulting density maps have been fitted with atomic models of...

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Vydáno v:J Struct Biol
Hlavní autoři: Paul, Danielle M., Squire, John M., Morris, Edward P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Academic Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367448/
https://ncbi.nlm.nih.gov/pubmed/28161413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2017.01.004
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