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Rac2 functions in both neutrophils and macrophages to mediate motility and host defense in larval zebrafish()

Leukocyte motility is required for host defense responses. Rac-family Rho GTPases are implicated in leukocyte function, however the distinct roles of different Rac isoforms in host defense in vivo have remained unclear. Here, we generated Rac2-deficient zebrafish using TALENs in order to directly co...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Rosowski, Emily E., Deng, Qing, Keller, Nancy P., Huttenlocher, Anna
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367389/
https://ncbi.nlm.nih.gov/pubmed/27837107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600928
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