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RNA G-quadruplexes are globally unfolded in eukaryotic cells and depleted in bacteria
In vitro, some RNAs can form stable four-stranded structures known as G-quadruplexes. Although RNA G-quadruplexes have been implicated in post-transcriptional gene regulation and diseases, direct evidence for their formation in cells has been lacking. Here, we identified thousands of mammalian RNA r...
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| 出版年: | Science |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5367264/ https://ncbi.nlm.nih.gov/pubmed/27708011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf5371 |
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