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A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions

Integration of the intestinal epithelium and the mucosal immune system is critical for gut homeostasis. The intestinal epithelium is a functional barrier that secludes luminal content, senses changes in the gut microenvironment, and releases immune regulators that signal underlying immune cells. How...

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Опубликовано в: :Sci Rep
Главные авторы: Noel, Gaelle, Baetz, Nicholas W., Staab, Janet F., Donowitz, Mark, Kovbasnjuk, Olga, Pasetti, Marcela F., Zachos, Nicholas C.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366908/
https://ncbi.nlm.nih.gov/pubmed/28345602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45270
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