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The Colicin E1 TolC-Binding Conformer: Pillar or Pore Function of TolC in Colicin Import?

The mechanism by which the drug export protein TolC is utilized for import of the cytotoxin colicin E1 across the outer membrane and periplasmic space is addressed. Studies of the initial binding of colicin E1 with TolC, occlusion of membrane-incorporated TolC ion channels, and the structure underly...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Zakharov, Stanislav D., Wang, Xin S., Cramer, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366289/
https://ncbi.nlm.nih.gov/pubmed/27536862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00621
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