Sulforaphane Protects against High Cholesterol-Induced Mitochondrial Bioenergetics Impairments, Inflammation, and Oxidative Stress and Preserves Pancreatic β-Cells Function

Cholesterol plays an important role in inducing pancreatic β-cell dysfunction, leading to an impaired insulin secretory response to glucose. This study aimed to determine the protective effects of sulforaphane, a natural isothiocyanate Nrf2-inducer, against cholesterol-induced pancreatic β-cells dys...

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Detalles Bibliográficos
Publicado en:Oxid Med Cell Longev
Main Authors: Carrasco-Pozo, Catalina, Tan, Kah Ni, Gotteland, Martin, Borges, Karin
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366224/
https://ncbi.nlm.nih.gov/pubmed/28386307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3839756
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