Use of Optical Imaging Technology in the Validation of a New, Rapid, Cost-Effective Drug Screen as Part of a Tiered In Vivo Screening Paradigm for Development of Drugs To Treat Cutaneous Leishmaniasis

In any drug discovery and development effort, a reduction in the time of the lead optimization cycle is critical to decrease the time to license and reduce costs. In addition, ethical guidelines call for the more ethical use of animals to minimize the number of animals used and decrease their suffer...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Caridha, Diana, Parriot, Sandi, Hudson, Thomas H., Lang, Thierry, Ngundam, Franklyn, Leed, Susan, Sena, Jenell, Harris, Michael, O'Neil, Michael, Sciotti, Richard, Read, Lisa, Lecoeur, Herve, Hickman, Mark, Grogl, Max
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365718/
https://ncbi.nlm.nih.gov/pubmed/28137819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02048-16
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