Use of Optical Imaging Technology in the Validation of a New, Rapid, Cost-Effective Drug Screen as Part of a Tiered In Vivo Screening Paradigm for Development of Drugs To Treat Cutaneous Leishmaniasis

In any drug discovery and development effort, a reduction in the time of the lead optimization cycle is critical to decrease the time to license and reduce costs. In addition, ethical guidelines call for the more ethical use of animals to minimize the number of animals used and decrease their suffer...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Caridha, Diana, Parriot, Sandi, Hudson, Thomas H., Lang, Thierry, Ngundam, Franklyn, Leed, Susan, Sena, Jenell, Harris, Michael, O'Neil, Michael, Sciotti, Richard, Read, Lisa, Lecoeur, Herve, Hickman, Mark, Grogl, Max
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365718/
https://ncbi.nlm.nih.gov/pubmed/28137819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02048-16
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