Evolution of the Sterol Biosynthetic Pathway of Pythium insidiosum and Related Oomycetes Contributes to Antifungal Drug Resistance

Pythiosis is a life-threatening infectious disease caused by the oomycete Pythium insidiosum. Direct exposure to Py. insidiosum zoospores can initiate infections of the eye, limb, gastrointestinal tract, or skin/subcutaneous tissue. Treatments for pythiosis have mostly relied on surgery. Antifungal...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Lerksuthirat, Tassanee, Sangcakul, Areeporn, Lohnoo, Tassanee, Yingyong, Wanta, Rujirawat, Thidarat, Krajaejun, Theerapong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365696/
https://ncbi.nlm.nih.gov/pubmed/28115356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02352-16
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