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Enterocin AS-48 as Evidence for the Use of Bacteriocins as New Leishmanicidal Agents

We report the feasibility of enterocin AS-48, a circular cationic peptide produced by Enterococcus faecalis, as a new leishmanicidal agent. AS-48 is lethal to Leishmania promastigotes as well as to axenic and intracellular amastigotes at low micromolar concentrations, with scarce cytotoxicity to mac...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Abengózar, María Ángeles, Cebrián, Rubén, Saugar, José María, Gárate, Teresa, Valdivia, Eva, Martínez-Bueno, Manuel, Maqueda, Mercedes, Rivas, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365675/
https://ncbi.nlm.nih.gov/pubmed/28167557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02288-16
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