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Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity

Three new (1–3) and two known (4 and 5) cytotoxic cardiac glycosides were isolated and characterized from a medicinal plant, Streblus asper, collected in Vietnam, with six new and one known derivatives (5a–5g) synthesized from (+)-strebloside (5). A preliminary structure-activity relationship study...

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Détails bibliographiques
Publié dans:J Nat Prod
Auteurs principaux: Ren, Yulin, Chen, Wei-Lun, Lantvit, Daniel D., Sass, Ellen J., Shriwas, Pratik, Ninh, Tran Ngoc, Chai, Hee-Byung, Zhang, Xiaoli, Soejarto, Djaja D., Chen, Xiaozhuo, Lucas, David M., Swanson, Steven M., Burdette, Joanna E., Kinghorn, A. Douglas
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365359/
https://ncbi.nlm.nih.gov/pubmed/27983842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.6b00924
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