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Impaired Epidermal to Dendritic T-Cell Signaling Slows Wound Repair in Aged Skin

Aged skin heals wounds poorly, increasing susceptibility to infections. Restoring homeostasis after wounding requires the coordinated actions of epidermal and immune cells. Here we find that both intrinsic defects and communication with immune cells are impaired in aged keratinocytes, diminishing th...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Keyes, Brice E., Liu, Siqi, Asare, Amma, Naik, Shruti, Levorse, John, Polak, Lisa, Lu, Catherine P., Nikolova, Maria, Pasoli, Hilda Amalia, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364946/
https://ncbi.nlm.nih.gov/pubmed/27863246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.10.052
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