Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis

Fatty acid synthase (FASN) is a key anabolic enzyme for de novo fatty acid synthesis, which is important in the development of colon carcinoma. The high expression of FASN is considered a promising molecular target for colon cancer therapy. Emodin, a naturally occurring anthraquinone, exhibits an an...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Lee, Kyung Ha, Lee, Myung Sun, Cha, Eun Young, Sul, Ji Young, Lee, Jin Sun, Kim, Jin Su, Park, Jun Beom, Kim, Ji Yeon
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364834/
https://ncbi.nlm.nih.gov/pubmed/28260110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6254
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