Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo

BACKGROUND: DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not been explored. RESULTS: To investigate the occurrence of DNA methylation changes...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Maag, Jesper L. V., Kaczorowski, Dominik C., Panja, Debabrata, Peters, Timothy J., Bramham, Clive R., Wibrand, Karin, Dinger, Marcel E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364592/
https://ncbi.nlm.nih.gov/pubmed/28335720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3621-x
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