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Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments

Functions of septin cytoskeletal polymers in tumorigenesis are still poorly defined. Their role in the regulation of cytokinesis and cell migration were proposed to contribute to cancer associated aneuploidy and metastasis. Overexpression of Septin 9 (Sept9) promotes migration of cancer cell lines....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Verdier-Pinard, P., Salaun, D., Bouguenina, H., Shimada, S., Pophillat, M., Audebert, S., Agavnian, E., Coslet, S., Charafe-Jauffret, E., Tachibana, T., Badache, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364497/
https://ncbi.nlm.nih.gov/pubmed/28338090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44976
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