Calcium flux mediated by purified inositol 1,4,5-trisphosphate receptor in reconstituted lipid vesicles is allosterically regulated by adenine nucleotides.

When incorporated into lipid vesicles, the purified inositol 1,4,5-trisphosphate (IP3) receptor protein mediates 45Ca2+ flux. We observe a potent, selective allosteric regulation by ATP of IP3 actions on Ca2+ flux. The action of ATP is selective for adenine nucleotides with ADP and AMP less potent a...

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Bibliografiska uppgifter
Huvudupphovsmän: Ferris, C D, Huganir, R L, Snyder, S H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1990
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC53643/
https://ncbi.nlm.nih.gov/pubmed/2156262
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