Hepatic Transcriptomic Alterations for N,N-Dimethyl-p-toluidine (DMPT) and p-Toluidine after 5-day Exposure in Rats

N,N-dimethyl-p-toluidine (DMPT), an accelerant for methyl methacrylate monomers in medical devices, was a liver carcinogen in male and female F344/N rats and B6C3F1 mice in a 2-year oral exposure study. p-Toluidine, a structurally-related chemical, was a liver carcinogen in mice but not in rats in a...

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Publicado en:Arch Toxicol
Autores principales: Dunnick, June K., Shockley, Keith R., Morgan, Daniel L., Brix, Amy, Travlos, Gregory S., Gerrish, Kevin, Sanders, J. Michael, Ton, T. V., Pandiri, Arun R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364093/
https://ncbi.nlm.nih.gov/pubmed/27638505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1831-7
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